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KMID : 0882420150880020127
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Korean Journal of Medicine
2015 Volume.88 No. 2 p.127 ~ p.134
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Treatment of Heart Failure with Reduced Ejection Fraction: Current Update
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Park Jin-Joo
Choi Dong-Joo
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Abstract
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The prevalence of heart failure (HF) has been steadily increasing and it now creates an enormous social and economic burden. HF is a syndrome characterized by a high mortality rate, frequent hospitalization, a reduced quality of life, and a complex therapeutic regimen. In the last three decades, major progress in both the diagnosis and management of HF has taken place, and the pharmacologic and non-pharmacologic advances have led to a significant improvement in survival and symptoms in HF patients. After an accurate diagnosis, a proper HF management plan requires a multi-level team approach comprised of the correct combination of drug therapy, device therapy, and surgery, including heart transplantation. In this review, we focused on the pharmacologic and non-pharmacologic treatment strategies for HF with reduced ejection fraction. The goal was to develop treatment guidelines based on significant evidence derived from large clinical trials.
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KEYWORD
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Systolic heart failure, Practice guideline
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